From national HBV and HDV screenings to vaccination and treatment in healthcare workers: The Mauritanian pilot study

Hepatitis B and D infections are highly endemic in Mauritania, with prevalences ranging from 10 to 20%. With the present prospective transversal pilot study, we aimed evaluate of HBV, HCV, HDV healthcare workers (HCWs), offer treatment or vaccination as required. At inclusion, each HCW was screened for anti-HBc Ab (followed by HBsAg assay when positive). Additional biological analyses were performed + cases. Depending on results, HBV anti-viral offered. A total 3,857 HCWs included, whom 1,363 tested negative received full vaccination. Of 2,494 who positive Ab, 1,246 anti-HBs 418 HBsAg. Three HBeAg; 66 18 had DNA levels respectively > 2,000 20,000 IU/mL; 48 anti-HDV among RNA. HCV prevalence 0.5%. Only seven fulfilled criteria five them treated. Few Mauritania immunised against HBV. The observed this work similar those our earlier works, whereas active infection less high. a serious health concern Mauritania. New recommendations developed accordance WHO guidelines should include mandatory screening immunisation HCWs.